J Korean Med Sci.  2014 Feb;29(2):164-171. 10.3346/jkms.2014.29.2.164.

Prevention of Venous Thromboembolism, 2nd Edition: Korean Society of Thrombosis and Hemostasis Evidence-Based Clinical Practice Guidelines

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
  • 2Department of Internal Medicine, School of Medicine, CHA University, Seongnam, Korea. doh@cha.ac.kr
  • 3Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul, Korea.
  • 4Department of Internal Medicine, Chonbuk National University Medical School, Jeonju, Korea.
  • 5Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
  • 6Department of Internal Medicine, VHS Medical Center, Seoul, Korea.
  • 7Department of Internal Medicine, Soonchunhyang University College of Medicine, Gumi, Korea.
  • 8Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea.
  • 9Department of Internal Medicine, Dong-A University College of Medicine, Busan, Korea.
  • 10Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea.
  • 11Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.
  • 12Department of Internal Medicine, Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.
  • 13Department of Internal Medicine, Sungkyunkwan University school of medicine, Samsung Medical Center, Seoul, Korea.
  • 14Medical Research Collaborating Center, Seoul National University Hospital, Seoul, Korea.
  • 15Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.

Abstract

In 2010, we proposed the first Korean Guidelines for the Prevention of Venous Thromboembolism (VTE). It was applicable to Korean patients, by modifying the contents of the second edition of the Japanese guidelines for the prevention of VTE and the 8th edition of the American College of Chest Physicians (ACCP) evidence-based clinical practice guidelines. From 2007 to 2011, we conducted a nationwide study regarding the incidence of VTE after major surgery using the Health Insurance Review and Assessment Service (HIRA) database. In addition, we have considered the 9th edition of the ACCP Evidenced-Based Clinical Practice Guidelines, published in 2012. It emphasized the importance of clinically relevant events as opposed to asymptomatic outcomes with preferences for both thrombotic and bleeding outcomes. Thus, in the development of the new Korean guidelines, three major points were addressed: 1) the new guidelines stratify patients into 4 risk groups (very low, low, moderate, and high) according to the actual incidence of symptomatic VTE from the HIRA databases; 2) the recommended optimal VTE prophylaxis for each group was modified according to condition-specific thrombotic and bleeding risks; 3) guidelines are intended for general information only, are not medical advice, and do not replace professional medical care and/or physician advice.

Keyword

Guideline; Prevention; Venous Thromboembolism; Bleeding

MeSH Terms

Age Factors
Anticoagulants/adverse effects/*therapeutic use
Asian Continental Ancestry Group
Evidence-Based Medicine
Heparin, Low-Molecular-Weight/therapeutic use
Humans
*Mechanical Thrombolysis
Neoplasms/complications/surgery
Republic of Korea
Risk Assessment
Surgical Procedures, Operative/adverse effects
Venous Thromboembolism/etiology/prevention & control/*therapy
Anticoagulants
Heparin, Low-Molecular-Weight

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