J Korean Med Sci.  2013 Mar;28(3):424-430. 10.3346/jkms.2013.28.3.424.

Reference Values for the Pulmonary Function of Korean Adults Using the Data of Korea National Health and Nutrition Examination Survey IV (2007-2009)

• Eom SY
• Kim H

• KMID: 1786941
• DOI: http://doi.org/10.3346/jkms.2013.28.3.424

Abstract

The objective of this study was to develop new spirometric reference equations for the Korean population using the raw data of the fourth Korea National Health and Nutrition Examination Survey (KNHANES IV, 2007-2009). A total of 4,753 healthy lifelong nonsmokers without respiratory diseases and symptoms were selected as the reference population. Spirometric reference equations were derived through multiple regression analysis. The newly developed reference equations for spirometry parameters were as follows: FEV1 (L) = -0.00025410 x (Age [years])2 + 0.00012644 x (Height [cm])2 - 0.00262 x Weight (kg) + 0.61493 (Men); FEV1 (L) = -0.00017538 x Age2 + 0.00009598 x Height2 - 0.00231 x Weight + 0.46877 (Women); FVC (L) = -0.00000219 x Age3 + 0.0000006995642 x Height3 + 1.19135 (Men); FVC (L) = 0.0167 x Age - 0.00030284 x Age2 + 0.0000005850287 x Height3 + 0.77609 (Women); FEV1/FVC (%) = -0.00289 x Age2 - 0.16158 x Height3 + 114.13736 (Men); FEV1/FVC (%) = -0.21382 x Age - 0.00000143 x Height3 + 97.62514 (Women). The newly developed spirometric reference equation in this study can be used as criteria for the interpretation of spirometry results and the diagnosis of respiratory diseases in Korean adults.

Keyword

Reference Values; Spirometry; Respiratory Function Test; Forced Expiratory Volume; Vital Capacity

MeSH Terms

Adult
Aged
*Algorithms
Asian Continental Ancestry Group
Female
Forced Expiratory Volume/physiology
Humans
Male
Middle Aged
*Nutrition Surveys
Reference Values
Regression Analysis
Republic of Korea
Spirometry/*standards
Young Adult

Figure

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  Fig. 1 Predicted of FEV1 using reference equations from the present study and other studies for males (A) and females (B) of average height and weight.

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  Fig. 2 Predicted of FVC using reference equations from the present study and other studies for males (A) and females (B) of average height.

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