J Korean Med Sci.  2010 Sep;25(9):1272-1276. 10.3346/jkms.2010.25.9.1272.

Seroprevalence of Tissue Invading Parasitic Infections Diagnosed by ELISA in Korea

  • 1Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Korea. hyekim@cau.ac.kr
  • 2Department of Medical Environmental Biology, Chung-Ang University College of Medicine, Seoul, Korea.


Seroprevalence of the IgG antibodies for Clonorchis sinensis, Paragonimus westermani, Taenia solium metacestode (cysticercus), and Spirometra erinacei plerocercoid (sparganum) was measured using enzyme-linked immunosorbent assay (ELISA) in sera of patients in Korea from 1993 to 2006. A total of 74,448 specimens referred nationwide from 121 hospitals revealed an IgG positive rate of 7.6% for the 4 parasites. The IgG positive rate (18.7%) for the 4 parasites in 1993 decreased gradually to 6.6% in 2006. Individual positive rate decreased from 5.2% (1993) to 1.6% (2006) for C. sinensis, from 2.8% (1993) to 1.1% (2006) for P. westermani, from 8.3% (1993) to 2.2% (2006) for cysticercus, and from 2.6% (1993) to 1.6% (2006) for sparganum. The positive rate was highest (21.2%) in the group of patients who ranged in age from 50-59 yr old, and in the group that was referred from the Seoul area (55.9%). In conclusion, our results suggest that tissue invading parasitic infections should always be included in differential diagnosis for patients with eosinophilia associated lesions of the central nervous system, liver, and lungs in Korea.


Seroepidemiologic Studies; Tissue Invading Parasitic Infections; Enzyme-Linked Immunosorbent Assay; Clonorchis sinensis; Paragonimus westermani; Taenia solium metacestode; Spirometra erinacei Plerocercoid
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