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J Korean Med Sci.  2004 Feb;19(1):130-133. 10.3346/jkms.2004.19.1.130.

A Case of Hodgkin's Lymphoma Associated with Sensory Neuropathy

Affiliations
  • 1Department of Neurology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. kkkim@www.amc.seoul.kr
  • 2Department of Diagnostic Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Abstract

Peripheral neuropathies occur in lymphoma patients. Causes of neuropathy include chemotherapy, opportunistic infections, and the lymphoma itself. We report a patient with lymphoma whose chief complaint was a sensory loss in the hands and feet. Electrophysiologic studies and sural nerve biopsy showed sensory polyneuropathies. We hypothesize that this neuropathy is associated with lymphoma-related ganglionopathy, and among the possible causes, we suspect that a systemic cause such as a paraneoplastic syndrome is the most likely pathogenic etiology. However, further follow-up will be necessary to see whether sensory symptoms change with lymphoma treatment.

Keyword

Lymphoma; Polyneuropathies; Paraneoplastic Syndromes

MeSH Terms

Adult
Biopsy
Electrophysiology
Hodgkin Disease/*complications/*diagnosis
Human
Lymphatic Metastasis
Lymphoma/*metabolism
Male
Peripheral Nervous System Diseases/*complications/*pathology
Sensation Disorders/complications/pathology
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