Neurointervention.  2013 Sep;8(2):92-100. 10.5469/neuroint.2013.8.2.92.

Computational Fluid Dynamics of Intracranial and Extracranal Arteries using 3-Dimensional Angiography: Technical Considerations with Physician's Point of View

• Park ST
• Yoon K
• Ko YB
• Suh DC

• KMID: 1784025
• DOI: http://doi.org/10.5469/neuroint.2013.8.2.92

Abstract

We investigate the potentials and limitations of computational fluid dynamics (CFD) analysis of patient specific models from 3D angiographies. There are many technical problems in acquisition of proper vascular models, in pre-processing for making 2D surface and 3D volume meshes and also in post-processing steps for display the CFD analysis. We hope that our study could serves as a technical reference to validating other tools and CFD results.

Keyword

Hemodynamics; Angiography; Carotid Arteries

MeSH Terms

Angiography
Arteries
Carotid Arteries
Hemodynamics
Humans
Hydrodynamics

Figure

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  Fig. 1 Work flow of Computational fluid analysis.

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  Fig. 2 A. Original surface mesh. B. After smoothening. C, D. Various size of triangular mesh by modifying quality threshold and maximum edge length.

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  Fig. 3 69-year-old male with past history of coronary stenting. A. Original 3D angiogram of common carotid arteriography with tight stenosis in proximal internal carotid artery. B. Edited 3D model before transferring to CFD analysis.

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  Fig. 4 35-year-old male presented with subarachnoid hemorrhage. A. Original 3D model, A-com aneurysm noted. B, C. Removing the un-wanted small vessels for CFD analysis using VOI (volume of interest, seeing as yellow lines) punching tools. D. Final vessel model.

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  Fig. 5 65-old-female presented with subarachnoid hemorrhage. A. Right internal carotid angiogram shows right MCA bifurcation aneurysm (arrow). B. 3D angiography from non-susbtracted distal radiography shows stenotic lesion in MCA (arrow) and petrous carotid artery (double arrow). C. Cutting surface of distal cervical ICA (arrow) show hole like structure due to laminar flow between contrast and contrast non-opacified blood.

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  Fig. 6 41-old-male presented with chief complaint of seizure. A. CT angiogram shows saccular aneurysm in basilar tip. B. Right vertebral arteriography shows laminar flow in basilar artery. C, D. Basilar tip aneurysm shows donut-shaped filling defect due to non-opacified blood.

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  Fig. 7 A. Cutting surface of posterior communicating artery show ragged mesh surface. B. Approximated A2 segment of anterior communicating artery looks like bi-lobulated single vessel lumen on surface mesh model. C. Cutting surface of vessel outlet show ragged margin which produce difficulties in boundary definition. There are also showing irregularities of triangle size.

Reference

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