J Korean Med Sci.  2006 Apr;21(2):355-357. 10.3346/jkms.2006.21.2.355.

Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with Idiopathic Thrombocytopenic Purpura: A Case Report

Affiliations
  • 1Department of Internal Medicine, Gyeongju Hospital, Dongguk University School of Medicine, Gyeongju, Korea. ptca@dumc.or.kr

Abstract

Acute myocardial infarction (AMI) is rare in patients with idiopathic thrombocytopenic purpura (ITP). We describe a case of an AMI during thrombocytopenia in a patient with chronic ITP. A 47-yr-old woman presented with anterior chest pain and a low platelet count (21,000/microliter) at admission. Urgent coronary angiography revealed total occlusion of proximal right coronary artery and primary percutaneous coronary intervention (PCI) was performed successfully. This case suggests that primary PCI may be a therapeutic option for an AMI in patients with ITP, even though the patient had severe thrombocytopenia.

Keyword

Myocardial Infarction; Percutaneous Coronary Intervention; Purpura; Thrombocytopenic; Idiopathic

MeSH Terms

Purpura, Thrombocytopenic, Idiopathic/*complications/drug therapy
Myocardial Infarction/*complications/*therapy
Middle Aged
Immunoglobulins, Intravenous/administration & dosage/adverse effects
Humans
Heparin/administration & dosage/adverse effects
Female
Anticoagulants/administration & dosage/adverse effects
*Angioplasty, Transluminal, Percutaneous Coronary

Figure

  • Fig. 1 Electrocardiogram shows the first degree atrioventricular block and ST segment elevation in leads of II, III, and aVF.

  • Fig. 2 Coronary angiography of the right coronary artery on left anterior oblique view. (A) Total obstruction in the proximal right coronary artery before percutaneous coronary intervention (PCI). (B) After the PCI with the aid of temporary pacemaker, successful reperfusion was obtained without residual stenosis.


Reference

1. Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med. 2002. 346:995–1008.
Article
2. Juhan-Vague I. Haemostatic parameters and vascular risk. Atherosclerosis. 1996. 124:Suppl. 49–55.
Article
3. Paolini R, Fabris F, Cella G. Acute myocardial infarction during treatment with intravenous immunoglobulin for idiopathic thrombocytopenic purpura. Am J Hematol. 2000. 65:177–178.
4. Elkayam O, Paran D, Milo R, Davidovitz Y, Almoznino-Sarafian D, Zeltser D, Yaron M, Caspi D. Acute myocardial infarction associated with high dose intravenous immunoglobulin infusion for autoimmune disorders. A study of four cases. Ann Rheum Dis. 2000. 59:77–80.
Article
5. Antman EM. Zipes Douglas P., Peter Libby, Bonow Robert O., Braunwald E, editors. ST-elevation myocardial infarction: Management. Heart Disease: Textbook of Cardiovascular Medicine. 2005. Vol 2:7th ed. Philadelphia: Saunders;1167–1226.
6. Fuchi T, Kondo T, Sase K, Takahashi M. Primary percutaneous transluminal coronary angioplasty performed for acute myocardial infarction in a patient with idiopathic thrombocytopenic purpura. Jpn Circ J. 1999. 63:133–136.
Article
7. Kikuchi S, Hayashi Y, Fujioka S, Kukita H, Ochi N. A case of intracoronary stent implanted for acute myocardial infarction in an elderly patient with idiopathic thrombocytopenic purpura. Nippon Ronen Igakkai Zasshi. 2002. 39:88–93.
Article
8. Paolini R, Zamboni S, Ramazzina E, Zampieri P, Cella G. Idiopathic thrombocytopenic purpura treated with steroid therapy does not prevent acute myocardial infarction: a case report. Blood Coagul Fibrinolysis. 1999. 10:439–442.
9. Fruchter O, Blich M, Jacob G. Fatal acute myocardial infarction during severe thrombocytopenia in a patient with idiopathic thrombocytopenic purpura. Am J Med Sci. 2002. 323:279–280.
Article
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