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J Korean Med Sci.  2010 Mar;25(3):501-504. 10.3346/jkms.2010.25.3.501.

Three Cases of Moraxella osloensis Meningitis: A Difficult Experience in Species Identification and Determination of Clinical Significance

Affiliations
  • 1Department of Laboratory Medicine, Korea University College of Medicine, Seoul, Korea.
  • 2Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea. leekcp@yuhs.ac
  • 3Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

We had three cases of Moraxella osloensis meningitis. The species identification was impossible by conventional and commercial phenotypic tests. However, we could identify the species using the 16S rRNA gene sequencing. Determination of clinical significance was difficult in one patient. All three patients recovered by appropriate antimicrobial therapy.

Keyword

Moraxella osloensis; Meningitis; 16S Ribosomal RNA Gene Sequencing

MeSH Terms

Adolescent
Aged, 80 and over
Anti-Bacterial Agents/therapeutic use
*Bacterial Typing Techniques
Child, Preschool
Female
Humans
Male
Meningitis, Bacterial/drug therapy/*microbiology
Moraxella/*pathogenicity
Moraxellaceae Infections/drug therapy/*microbiology
RNA, Bacterial/analysis
RNA, Ribosomal, 16S/analysis
Anti-Bacterial Agents
RNA, Bacterial
RNA, Ribosomal, 16S
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