J Korean Med Sci.  2014 Apr;29(4):462-467. 10.3346/jkms.2014.29.4.462.

Clinical Application of Adipose Stem Cells in Plastic Surgery

Affiliations
  • 1Department of Pathology, College of Medicine, Yeungnam University, Daegu, Korea.
  • 2Oblige Plastic Surgery Clinic, Daegu, Korea. originaljjh@me.com

Abstract

Adipose stem cells (ASCs) are a type of adult stem cells that share common characteristics with typical mesenchymal stem cells. In the last decade, ASCs have been shown to be a useful cell resource for tissue regeneration. The major role of regenerative medicine in this century is based on cell therapy in which ASCs hold a key position. Active research on this new type of adult stem cell has been ongoing and these cells now have several clinical applications, including fat grafting, overcoming wound healing difficulties, recovery from local tissue ischemia, and scar remodeling. The application of cultured cells will increase the efficiency of cell therapy. However, the use of cultured stem cells is strictly controlled by government regulation to ensure patient safety. Government regulation is a factor that can limit more versatile clinical application of ASCs. In this review, current clinical applications of ASCs in plastic surgery are introduced. Future stem cell applications in clinical field including culturing and banking of ASCs are also discussed in this review.

Keyword

Adult Stem Cells; Adipose Stem Cells; Mesenchymal Stem Cells; Stromal Cells; Wound Healing; Regeneration; Adipose Tissue; Ischemia; Tissue Engineering; Cell Therapy

MeSH Terms

Adipose Tissue/*cytology
Cicatrix/prevention & control
Humans
Ischemia/therapy
*Mesenchymal Stem Cell Transplantation
Mesenchymal Stromal Cells/*cytology
Surgery, Plastic
Tissue Engineering
Wound Healing
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