J Korean Burn Soc.  2011 Jun;14(1):35-38.

Extremity Operation by a Use of Fibrin Sealant in Burn Patient

• Cho YS
• Yang HT
• Lim HJ
• Kim D
• Hur J
• Chun W
• Kim JH
• Lee BC
• Seo CH
• Choi JT

Abstract

PURPOSE
The surgical treatment of burn patient is associated with substantial blood loss. Therefore, multiple hemostatic techniques have been proposed for this problem. Unfortunately, a clear conclusion as to the best hemostatic agent cannot be made. Then, we present our experience of using Fibrin sealant (TISSEEL(TM)) in extremity operation.
METHODS
We reviewed the medical records of 10 patients treated in our burn center who conducted the extremity operation using Fibrin sealant from January 2010 to December 2010.
RESULTS
The mean tourniquet time is within 60 minutes and no need of transfusion during the operation in all patients. The average take rate for skin graft is over the 98%. No one has nerve injury and other problems.
CONCLUSION
Fibrin sealant is a human derived factors that are designed to reproduce the final step of the physiologic coagulation cascade of a stable fibrin clot. In addition, Fibrin sealant has the advantage of being biocompatible and biodegradable, without inducing inflammation, foreign body reaction, and tissue necrosis. Fibrin sealant is shown to be effective methods to achieve hemostasis for the extremity burn surgery.

Keyword

Burn; Fibrin sealants; Hemostasis

MeSH Terms

Burn Units
Burns
Extremities
Fibrin
Fibrin Tissue Adhesive
Foreign-Body Reaction
Hemostasis
Hemostatic Techniques
Humans
Imidazoles
Inflammation
Medical Records
Necrosis
Nitro Compounds
Skin
Tourniquets
Transplants
Fibrin
Fibrin Tissue Adhesive
Imidazoles
Nitro Compounds