Korean J Ophthalmol.  1995 Dec;9(2):111-116. 10.3341/kjo.1995.9.2.111.

Change of refraction in premature infants after cryotherapy for retinopathy of prematurity between the age of six months and three years

Affiliations
  • 1Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

To investigate the chronological change of refraction in premature infants after cryotherapy for retinopathy of prematurity (ROP), cycloplegic refractions had been performed at 6 months and 3 years after term in premature infants who underwent cryotherapy for ROP. The changes of refractions between the two study ages were evaluated not only in the total cryo-treated eyes, but also in the subdivided groups according to the posterior pole appearances. In the total 61 eyes of 32 premature infants, mean spherical equivalents were -4.05D vs. -5.94D (6 months vs. 3 years) (p = 0.0001). In the normal posterior pole group (48 eyes), mean spherical equivalents were -3.45D vs. -5.68D (6 months vs. 3 years) (p = 0.0000), and in the abnormal posterior pole group (13 eyes), -6.28D vs. -6.86D (6 months vs. 3 years) (p = 0.6496). These results mean that there is a myopic progressive change between 6 months and 3 years after term in the cryo-treated eyes for acute ROP and it is more evident in the eyes with normal posterior pole.

Keyword

cryotherapy; myopic progressive change; posterior pole appearance; cycloplegic refraction; retinopathy of prematurity

MeSH Terms

Acute Disease
Child, Preschool
Cryosurgery/*adverse effects
Follow-Up Studies
Gestational Age
Humans
Infant
Infant, Newborn
*Infant, Premature
Myopia/*etiology/physiopathology
*Refraction, Ocular
Retinopathy of Prematurity/physiopathology/*surgery
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