Korean J Ophthalmol.  1993 Jun;7(1):11-15. 10.3341/kjo.1993.7.1.11.

Effects of sodium hyaluronate on filtration bleb in rabbits

Affiliations
  • 1Department of Ophthalmology, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, Korea.
  • 2Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.
  • 3Department of Ophthalmology, College of Medicine, Chungbuk National University, Cheongju, Korea.
  • 4Glaucoma Service, Dr. Hong's Eye Clinic, Seoul, Korea.

Abstract

Sodium hyaluronate can be used during a trabeculectomy to prevent early postoperative hypotony and shallow anterior chamber. To determine its long-term effect on the outcome of filtration surgery, fifteen rabbits underwent a osterior-lip sclerectomy in both eyes. Into their right eyes 0.2ml sodium hyaluronate, and into left eyes 0.2ml balanced salt solution were injected intracamerally. Gross and histopathological differences of bleb were observed. There was no statistically significant difference in longevity of the filtration bleb.

Keyword

filtration bleb; hypotony; Sodium hyaluronate; posterior-lip sclerectomy; rabbits

MeSH Terms

Animals
Anterior Chamber/*drug effects/pathology
Conjunctiva/pathology
Connective Tissue/pathology
Follow-Up Studies
Hyaluronic Acid/*administration & dosage
Ocular Hypotension/prevention & control
Rabbits
Sclera/pathology
*Sclerostomy
Hyaluronic Acid
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