J Korean Soc Pediatr Nephrol.  2014 Oct;18(2):123-127. 10.3339/jkspn.2014.18.2.123.

Three Cases of Erythema Multiforme Developed during Deflazacort Therapy in Children with Nephrotic Syndrome

• Lee SJ
• Kang BH
• Cho MH

• KMID: 1733226
• DOI: http://doi.org/10.3339/jkspn.2014.18.2.123

Abstract

Erythema multiforme (EM) is an acute mucocutaneous disorder involving the skin, mouth, eyes, and genital organs. It is classified into EM minor and EM major according to the involvement of the mucosal membrane. Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN) belong to EM major. Compared to EM minor, SJS presents with more severe and progressive symptoms, and has a higher mortality rate. Corticosteroids are used in the treatment of EM. We report three cases of EM (two cases of EM minor and one case of SJS) that developed during treatment with oral corticosteroid (deflazacort; Calcort(R)) in children with nephrotic syndrome.

Keyword

Erythema multiforme; Stevens-Johnson syndrome; Nephrotic syndrome; Deflazacort

MeSH Terms

Adrenal Cortex Hormones
Child*
Erythema Multiforme*
Genitalia
Humans
Membranes
Mortality
Mouth
Necrosis
Nephrotic Syndrome*
Skin
Stevens-Johnson Syndrome
Adrenal Cortex Hormones