Korean J Otorhinolaryngol-Head Neck Surg.  2010 May;53(5):320-323. 10.3342/kjorl-hns.2010.53.5.320.

A Case of Aggressive Local Recurrence of Metastasizing Pleomorphic Adenoma with Multiple Lung Metastases

Affiliations
  • 1Department of Otolaryngology-Head and Neck Surgery, Chonbuk National University School of Medicine, Jeonju, Korea. imaima97@naver.com

Abstract

Metastasizing pleomorphic adenoma is a rare condition of metastasis from a histologically benign salivary gland tumor. It usually occurs after multiple local recurrences, between 3 to 52 years after the occurrence of the primary lesion. No histologic or molecular parameters exist at the present time that could predict the development of metastasis in these neoplasms. Also, there is no definite treatment protocol available in cases of widespread metastasis. We report a case of metastasizing pleomorphic adenoma presenting with aggressive recurrence and multiple bilateral lung metastases that resulted despite surgery and chemotherapy. Clinical aspects of this disease is discussed.

Keyword

Pleomorphic adenoma; Metastasis; Neoplasm recurrence; Local

MeSH Terms

Adenoma, Pleomorphic
Clinical Protocols
Lung
Neoplasm Metastasis
Recurrence
Salivary Glands
Full Text Links
  • KJORL-HN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error