Korean J Pediatr Infect Dis.  2014 Aug;21(2):96-103.

Comparison of Group A, B and C Rotaviral Gastroenteritis among Children in Korea: Prevalence and Clinical Features

• Bae KS
• Bae WR
• Kim JH
• Bin JH
• Kim HH
• Lee HJ
• Lee W

Abstract

PURPOSE
The aim of this study is that the prevalence of rotavirus infection was evaluated by each group and clinical features of group A, B and C rotaviruses infections were described respectively to compare one with another.
METHODS
Between January 2010 and December 2010, we enrolled a group of children below 10 years of age admitted for management of acute diarrhea at the Catholic University of Korea Bucheon St. Mary's Hospital. A total of 310 stool samples documented to be free of common bacterial pathogens were collected from children with diarrhea. The presence of group A, B or C rotavirus is indicated by amplification of DNA segments of the expected lengths after the first and second PCRs.
RESULTS
In a total of 310 stool specimens, 40 (12.9%) specimens were positive for rotaviruses. These included 23 (7.4%) positive for group A, 5 (1.6%) for group B and 12 (3.9%) for group C rotaviruses. Group B rotavirus infected patients had significantly less diarrheas per day (group A: P=0.01, group C: P=0.01) and shorter duration of vomiting days (group A: P=0.03, group C: P=0.03) than those with group A and C rotaviruses infection respectively. All the group B rotaviruses had been isolated in March and October. Group C rotavirus infections were prevalent during late summer and early winter and peaked in October.
CONCLUSION
These findings indicate that group B and C rotaviruses are notable causes or the contributing causes of diarrhea among infants and children in Korea.

Keyword

Rotavirus; Gastroenteritis; Prevalence

MeSH Terms

Child*
Diarrhea
DNA
Gastroenteritis*
Gyeonggi-do
Humans
Infant
Korea
Polymerase Chain Reaction
Prevalence*
Rotavirus
Rotavirus Infections
Vomiting
DNA

Figure

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  Fig. 1. PCR primers for detection of rotavirus groups A, B and C.

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  Fig. 2. Monthly distribution of group A, B and C rotavirus-positive cases in Korea.

Reference

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