Korean J Dermatol.  2014 Aug;52(8):567-570.

Abrupt Onset of Palisaded Neutrophilic and Granulomatous Dermatitis in a Patient with Rheumatoid Arthritis

• Choi SH
• Ha SM
• Ko DY
• Song KH
• Kim KH

Abstract

Palisaded neutrophilic and granulomatous dermatitis (PNGD) is characterized histopathologically by the presence of granulomatous inflammation with or without leukocytoclastic vasculitis. It has been associated with multiple systemic diseases, particularly autoimmune conditions like rheumatoid arthritis and Behcet's disease. We report a 52-year-old woman with rheumatoid arthritis who presented with a single, non-tender, rapidly growing nodule on her right elbow. Histologic examination of the nodule revealed degenerated collagen, neutrophils, neutrophilic dust, fibrin, and mucin present in the centers of the palisades of histiocytes throughout the dermis. Herein, we report the abrupt onset of PNGD in a patient with rheumatoid arthritis.

Keyword

Abrupt onset; Palisaded neutrohpilic and granulomatous dermatitis; Rheumatoid arthritis

MeSH Terms

Arthritis, Rheumatoid*
Collagen
Dermatitis*
Dermis
Dust
Elbow
Female
Fibrin
Histiocytes
Humans
Inflammation
Middle Aged
Mucins
Neutrophils*
Vasculitis
Collagen
Dust
Fibrin
Mucins