Korean J Gastroenterol.  2011 Aug;58(2):100-102. 10.4166/kjg.2011.58.2.100.

A Case of Chemical Colitis Caused by Hydrogen Peroxide Enema

• Lim CH
• Lee HY
• Kim WC
• Cho SH
• Jeong HS
• Jeon YJ
• Lee JE
• Kim SW

• KMID: 1718417
• DOI: http://doi.org/10.4166/kjg.2011.58.2.100

Abstract

Hydrogen peroxide is commonly used as a disinfectant that has been reported to cause chemical colitis. We report a case of 49 year-old man who presented with chemical colitis caused by self-inflicted hydrogen peroxide enema. In the sigmoidoscopic examination, diffuse erythematous and edematous mucosal change with multiple ulcerations and easy touch bleeding was noted from the rectum to the proximal sigmoid colon. Abdominal computed tomography showed diffuse wall thickening of the rectum and the sigmoid colon with inflammatory and reactive change at surrounding. The patient was treated with NPO, intravenous fluid, and antibiotic therapy. On 5th hospital day, abdominal pain and bloody stool disappeared, and the patient started oral feeding. He discharged on 6th hospital day with fully recovered state.

Keyword

Hydrogen peroxide; Colitis

MeSH Terms

Abdominal Pain/etiology
Colitis/*chemically induced/therapy
Enema/*adverse effects
Gastrointestinal Hemorrhage/etiology
Humans
Hydrogen Peroxide/*adverse effects
Male
Middle Aged
Sigmoidoscopy
Tomography, X-Ray Computed

Figure

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  Fig. 1. Sigmoidoscopic findings. Diffuse erythematous and edematous mucosal change with multiple ulcerations and easy touch bleeding was noted from the rectum (A) to the proximal sigmoid colon (B, C). Mucosal pattern of the descending colon was normal (D).

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  Fig. 2. Abdominal CT scan findings. Abdominal CT showed diffuse wall thickening of the rectum and the sigmoid colon with inflammatory and reactive change at surrounding in cross-sectional view (A) and coronal view (B).

Reference

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