Korean J Intern Med.  2009 Sep;24(3):165-168. 10.3904/kjim.2009.24.3.165.

Autosomal Dominant Polycystic Kidney Disease: 2009 Update for Internists

Affiliations
  • 1Northwest Renal Clinic, Transplant Services, Portland, OR, USA. bennettw@lhs.org

Abstract

Because autosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic abnormalities seen in today's medical practice, many internists will likely treat patients affected by this condition. Genetic abnormalities have been increasingly recognized, and the pathophysiology of the disease is beginning to be unraveled. Because of advances in imaging technology, surrogate markers for disease progression have allowed clinical studies of newer therapeutic agents to proceed. In the near future, therapies for this common genetic disease may be available to either prevent or stabilize the disease course for many affected individuals.

Keyword

Polycystic kidney diseases; Hypertension; Tubule; Kidney; Genetic

MeSH Terms

Humans
*Polycystic Kidney, Autosomal Dominant/complications/diagnosis/genetics/therapy
Prognosis
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