Korean J Parasitol.  2013 Dec;51(6):759-761. 10.3347/kjp.2013.51.6.759.

Successful Treatment of Brugia pahangi in Naturally Infected Cats with Ivermectin

Affiliations
  • 1Parasitology Unit, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand. Piyanan.T@Chula.ac.th

Abstract

Lymphatic filariasis is a common parasitic disease of cats in tropical regions including Thailand. The objective of this study was to determine the efficacy of ivermectin against microfilariae of Brugia pahangi in naturally infected cats. Eight cats naturally infected with B. pahangi were divided into control (untreated) and treated groups. Cats in the latter group were given ivermectin injection at 400 microg/kg weekly for 2 months. Microfilariae were counted every week until 48 weeks. Microfilaremia was significantly decreased in the treated group 4 weeks after starting the treatment and become zero at week 9 and afterwards. On the other hand, cats in the control group had high microfilaremia throughout the study. It was successful to treat and control B. pahangi infection in naturally infected cats using ivermectin.

Keyword

Brugia pahangi; treatment; cat

MeSH Terms

Animals
Brugia pahangi/*isolation & purification
Cat Diseases/*drug therapy/*parasitology
Cats
Elephantiasis, Filarial/drug therapy/parasitology/*veterinary
Filaricides/*administration & dosage
Ivermectin/*administration & dosage
Parasite Load
Thailand
Treatment Outcome
Filaricides
Ivermectin
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