J Clin Neurol.  2007 Mar;3(1):50-52. 10.3988/jcn.2007.3.1.50.

Two Cases of Hypertensive Encephalopathy Involving the Brainstem

Affiliations
  • 1Department of Neurology, College of Medicine, Cheju National University, Jeju, Korea. neurokang@cheju.ac.kr

Abstract

Hypertensive encephalopathy is a medical emergency whose clinical manifestations are usually associated with bilateral parieto-occipital lesions. Predominant brainstem edema without accompanying occipital lesions is rare in hypertensive encephalopathy and usually occurs in patients with secondary hypertension. We describe the clinical and radiological features of two patients with reversible hypertensive brainstem encephalopathy. Both patients had chronic renal failure, but the extensive neuroimaging abnormalities revealed few clinical features of brainstem involvement. The clinical findings and neuroimaging abnormalities resolved once the hypertension was treated.

Keyword

Hypertension; Brainstem; Hypertensive encephalopathy

MeSH Terms

Brain Stem*
Edema
Emergencies
Humans
Hypertension
Hypertensive Encephalopathy*
Kidney Failure, Chronic
Neuroimaging

Figure

  • Figure 1 MRI images of case 1. Initial axial T2-weighted images (A, B). Normal intensity in the diffusion-weighted image and signals of increased intensity in the apparent diffusion coefficient mapping are present in the region of the high-intensity signal in the T2-weighted image (C, D). T2-weighted image at follow-up evaluation (E, F). Note the relative sparing of the posterior supratentorial regions (B).


Cited by  1 articles

Steroid-Responsive Recurrent Encephalopathy Associated with Subacute Thyroiditis
Yun Jae Chung, Kwang-Yeol Park, Jihyun Ahn, Sam-Yeol Ha, Young Chul Youn
J Clin Neurol. 2008;4(4):167-170.    doi: 10.3988/jcn.2008.4.4.167.


Reference

1. Zeigler DK, Zosa A, Zileli T. Hypertensive encephalopathy. Arch Neurol. 1965. 12:472–478.
Article
2. Venkata C, Ram S. Hypertensive encephalopathy: recognition and management. Arch Intern Med. 1978. 138:1851–1853.
Article
3. Gifford RW. Management of hypertensive crises. JAMA. 1991. 266:829–835.
Article
4. Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med. 1996. 334:494–500.
Article
5. Schwartz RB, Jones KM, Kalina P, Bajakian RL, Mantello MT, Garada B, et al. Hypertensive encephalopathy: findings on CT, MR imaging, and SPECT imaging in 14 cases. Am J Roentgenol. 1992. 159:379–383.
Article
6. Kang BW, Bae YJ, Cheon WH, Park SP, Suh CK. Two cases of hypertensive brainstem encephalopathy. J Korean Neurol Assoc. 2003. 21:535–538.
7. Thambisetty M, Biousse V, Newman NJ. Hypertensive brainstem encephalopathy: clinical and radiographic features. J Neurol Sci. 2003. 208:93–99.
Article
8. Cruz-Flores S, de Assis Aquino Gondim F, Leira EC. Brainstem involvement in hypertensive encephalopathy: clinical and radiological findings. Neurology. 2004. 62:1417–1419.
Article
9. Hauser RA, Lacey DM, Knight MR. Hypertensive encephalopathy. Magnetic resonance imaging demonstration of reversible cortical and white matter lesions. Arch Neurol. 1988. 45:1078–1083.
10. Covarrubias DJ, Luetmer PH, Campeau NG. Posterior reversible encephalopathy syndrome: prognostic utility of quantitative diffusion-weighted MR images. Am J Neuroradiol. 2002. 23:1038–1048.
11. de Seze J, Mastain M, Stojkovic T, Ferriby D, Pruvo JP, Destee A, et al. Unusual MR findings of the brainstem in arterial hypertension. Am J Neuroradiol. 2000. 21:391–394.
12. Schaefer PW, Buonanno FS, Gonzalez RG, Schwamm LH. Diffusion-weighted imaging discriminates between cytotoxic and vasogenic edema in a patient with eclampsia. Stroke. 1997. 28:1082–1085.
Article
13. Morello F, Marino A, Cigolini M, Cappellari F. Hypertensive brain stem encephalopathy: clinically silent massive edema of the pons. Neurol Sci. 2001. 22:317–320.
Article
Full Text Links
  • JCN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr