Korean J Dermatol.  1981 Aug;19(4):445-501.

Bullous Congenital Ichthyosiform Erythroderma: Report of a Case

Abstract

We present a case of bullous congenital ichthyosiform erythroderma in a two year old female, in whom no hereditary background was found. The skin lesion was characterized clinically by blister formation with generalized erythematous hyperkeratosis which was especially prominent on the flexural surfaces of extremities and intertriginous areas. The histopathologic examination revealed marked hyperkeratosis, cavity changes of the malpighian cells with perinuclear vacuoles and markedly thickened granular layer containing many keratohyaline granules.


MeSH Terms

Blister
Extremities
Female
Humans
Hyperkeratosis, Epidermolytic*
Skin
Vacuoles
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