Korean J Dermatol.  1978 Dec;16(6):507-511.

Two Cases of Epidermolysis Bullosa Simplex

• Byun JH
• Kook HI

Abstract

Epidermolysis Bullosa Simplex is characterized by autosomal dominant rnheritance, and chronic noninflammatory conditions in which the clinical lesions, erosion, blisters usually result from relatively minor mechanical trauma to the skin, especially joints of hands, elbows, knees, and feet and other sites subject to repeated trauma The lesiona are present or appeared after a few days after birth or shortly after especialy of the lower legs or feet, and not involved at naiIs or mucous membranes. Though infection is not common on the feet or hands, even infected lesions generally heal with out scarring. 2 cases of Epidermolysis bullosa simplex were experienced, the one was 5 month old male baby who had fresh vesiculobullous, hemorrhagic bulla, crusts, exfoliation, no nail dystrophy, since a few days after birth. The another was 5 month old female baby, who had pea sized tense bulla, and exfoliations on the hands and feet. Diagnosis confirmed by clinical features and histological findings. Literature were reviewed in comparison with mechanobulIous disease.

MeSH Terms

Blister
Cicatrix
Diagnosis
Elbow
Epidermolysis Bullosa Simplex*
Epidermolysis Bullosa*
Female
Foot
Hand
Humans
Infant
Joints
Knee
Leg
Male
Mucous Membrane
Parturition
Peas
Skin
Transcutaneous Electric Nerve Stimulation