Korean J Med.  2004 Apr;66(4):414-419.

A case of autoimmune chronic pancreatitis associated with sjogren's syndrome

• Kim SJ
• Kim MH
• Lee SS
• Song MH
• Lee SK
• Seo DW
• Min YI

Abstract

We report a case of autoimmune chronic pancreatitis associated with Sjogren's syndrome. A 68-year-old man was admitted to the hospital with jaundice. The serum IgG and IgE were elevated and endoscopic retrograde cholangiopancreatography demonstrated an irregular narrowing of the main pancreatic duct and stricture of the distal common bile duct. He complained of dry mouth and dry eyes with a gritty feeling. On physical examination, enlargement of both submandibular glands was noted. Schirmer test revealed positive result and the labial minor salivary gland biopsy showed infiltration of lymphocytes and plasma cells, consistent with Sjogren's syndrome. After one month of oral steroid therapy, the abnormalities in clinical, laboratory and radiological findings of autoimmune chronic pancreatitis were improved markedly. The enlargement of both submandibular glands was improved, too. To our knowledge, this is the first case of autoimmune chronic pancreatitis associated with Sjogren's syndrome in Korea.

Keyword

Autoimmune chronic pancreatitis; Sjogren's syndrome

MeSH Terms

Aged
Biopsy
Cholangiopancreatography, Endoscopic Retrograde
Common Bile Duct
Constriction, Pathologic
Humans
Immunoglobulin E
Immunoglobulin G
Jaundice
Korea
Lymphocytes
Mouth
Pancreatic Ducts
Pancreatitis, Chronic*
Physical Examination
Plasma Cells
Salivary Glands, Minor
Sjogren's Syndrome*
Submandibular Gland
Immunoglobulin E
Immunoglobulin G