Korean J Dermatol.  2006 Mar;44(3):341-345.

A Case of Vitamin K1 Dermatitis

Affiliations
  • 1Department of Dermatology, College of Medicine, Pusan National University, Busan, Korea. hsjang@pusan.ac.kr

Abstract

Vitamin K1 is a naturally-occurring vitamin used to treat certain coagulation disorders, and cutaneous adverse reaction to vitamin K1 are infrequently reported. The cutaneous adverse reaction caused by vitamin K1 is called vitamin K1 dermatitis, and includes erythematous plaques, peudoscleroderma, contact dermatitis on epicutaneously exposed skin, and localized urticarial lesions. Vitamin K1 dermatitis can easily be overlooked because of it's low incidence and various morphology, therefore, awareness of past history is important. Most cases of vitamin K1 dermatitis previously reported have been associated with liver diseases, primarily alcoholic liver cirrhosis and viral hepatitis. However vitamin K1 dermatitis can be seen, not only in patients with liver function disturbances, but also in patients without liver disease. We report a case of vitamin K1 dermatitis in a woman who had no liver dysfunction (confirmed by skin test).

Keyword

Skin test; Vitamin K1 dermatitis

MeSH Terms

Dermatitis*
Dermatitis, Contact
Female
Hepatitis
Humans
Incidence
Liver
Liver Cirrhosis, Alcoholic
Liver Diseases
Skin
Skin Tests
Vitamin K 1*
Vitamins*
Vitamin K 1
Vitamins
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