Tuberc Respir Dis.  2006 Jun;60(6):684-689. 10.4046/trd.2006.60.6.684.

A Case of Recurred Uterine Cervical Cancer Presented as Only Huge Mediastinal Mass

• Lee JS
• Gong SJ
• Joo JE
• Lee JA
• Kim JS
• Ahn YS

• KMID: 1630808
• DOI: http://doi.org/10.4046/trd.2006.60.6.684

Abstract

Uterine cervical cancer is the 5(th) most common malignancy in Korean women. With the development of new diagnostic and therapeutic modalities, earlier stage cancers are being diagnosed with longer survival rates being anticipated. Accordingly, recurrent cancers are being encountered more often in clinical practice. Most recurrent uterine cervical cancer patients, have intra-pelvic lesions and adjacent lymph node involvement, while a distant metastasis alone is extremely rare. A mediastinal recurrence of uterine cervical cancer is not common with most manifesting as small lymph node enlargements. We report a case of a 46-year-old woman with recurrent uterine cervical cancer presenting only as a huge mediastinal mass without a local recurrence.

Keyword

Mediastinal mass; Uterine cervical cancer; Recurrence

MeSH Terms

Female
Humans
Lymph Nodes
Middle Aged
Neoplasm Metastasis
Recurrence
Survival Rate
Uterine Cervical Neoplasms*

Figure

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  Figure 1 Chest PA showed linear atelectasis and calcification in left lower lung field.

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  Figure 2 Chest CT scan revealed anterior mediastinal mass and left pleural effusion.

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  Figure 3 Microscopic study revealed diffuse infiltrating squamous cell nests with central necrosis of squamous cell carcinoma, large cell nonkeratinizing type in the mediastinal mass (H&E stain, A: ×100, B: ×200) and the same type of squamous cell carcinoma of in the uterine cervix 4 years ago (H&E stain, C: ×100, D: ×200).

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  Figure 4 Human papilloma virus DNA chip sheet showed positivity for 16 genotype in mediastinal mass.

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