Korean J Gastrointest Endosc.  2003 Sep;27(3):137-142.

A Case of Mucosa-Associated Lymphoid Tissue Lymphoma in the Esophagus Accompanied by Bronchus-Associated Lymphoid Tissue Lymphoma

  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Gastroenterology, National Health Insurance Corporation Ilsan Hospital, Ilsan, Korea. cho6706@hanmail.net
  • 3Department of Hemato-oncology, National Health Insurance Corporation Ilsan Hospital, Ilsan, Korea.
  • 4Department of Clinical Pathology, National Health Insurance Corporation Ilsan Hospital, Ilsan, Korea.


Mucosa-associated lymphoid tissue (MALT) is specially adapted component of the immune system protecting the permeable surface of the gastrointestinal mucosa, bronchial mucosa and other mucosa. Chronic infection of the stomach by Helicobacter pylori, Hashimoto's thyroiditis, Sjogren syndrome in the salivary gland and other chronic inflammatory and autoimmune disease lead to the accumulation of MALT in the mucosa and MALT lymphoma arises from this acquired MALT. MALT lymphoma is histologically characterized by proliferation of centrocyte-like cells that invade the epithelium and lymphoepithelial lesion form. Gastrointestinal MALT lymphoma is clinically important because it is a localized, slow progressive disease and has a long survival and favorable clinical course compared with other lymphoma. Esophageal MALT lymphoma is extremely rare, so we report, radiologic, endoscopic and pathological findings and clinical course in a case of esophageal MALT lymphoma with brouchas-associated lymphoid tissue (BALT) lymphoma with a review of literature.


Esophagus; Lymphoma; Mucosa-associated lymphoid tissue
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