Korean J Dermatol.  2002 Apr;40(4):405-409.

A Case of Primary Cutaneous Plasmacytoma

• Kim D
• Yoon KH

Abstract

Primary cutaneous plasmacytoma is a rare cutaneous B cell lymphoma characterized by monoclonal proliferation of mature plasma cells in the skin without systemic involvement. Although a significant proportion of patients, especially with multiple lesions, went on to develop systemic disease with a poor prognosis, the abnormal clone of plasma cells may arise in the skin and never progress to multiple myeloma involving the bone marrow in a number of patients. We report a case of primary cutaneous plasmacytoma and review data published in the literature. A 19-year-old man developed multiple 0.2 to 0.5cm sized erythematous grouped papules on his posterior neck for 4 years. Histopathologic examination represented superficial and deep interstitial and nodular dense infiltration of plasma cells showing monoclonal expression of immunoglobulin lambda light chain. F-18 FDG coincidence PET(CoDe-PET) scan and serum electrophoresis were within normal limit. Any systemic disease has not developed for 6 months after diagnosis.

Keyword

Primary cutaneous plasmacytoma; Monoclonality; Lambda chain

MeSH Terms

Bone Marrow
Clone Cells
Diagnosis
Electrophoresis
Humans
Immunoglobulins
Lymphoma, B-Cell
Multiple Myeloma
Neck
Plasma Cells
Plasmacytoma*
Prognosis
Skin
Young Adult
Immunoglobulins