Korean J Dermatol.  2002 Apr;40(4):386-392.

A Clinical Study of Facial Wrinkles Affected by Facial Expression Muscles Treated with Botulinum Toxin(Botox(R))

• Youn SW
• Seo KI
• Yoo JY
• Park KC
• Eun HC

Abstract

BACKGROUND: Botulinum toxin type A is being widely used for the treatment of facial wrinkles affected by facial expression muscles. Due to the sudden and exponential surge in popularity of its use for facial wrinkles, there are scanty reports of facial wrinkles treated with botulinum toxin type A especially in Asians.
OBJECTIVE
This study was performed to investigate the clinical features of facial wrinkles affected by facial expression muscles and the effects of botulinum toxin A on the treatment of wrinkles.
METHODS
Medical records of 61 patients with facial wrinkles treated with botulinum toxin type A were reviewed. Demographic profiles of the patients, the age of onset of facial wrinkle, the distributions of facial wrinkles, treatment dose of botulinum toxin type A, side effects, and follow up data were analyzed.
RESULTS
Female patients were predominant(93.4%) than male patients(6.6%). The mean age of the patients was 41.3 years. Crow's feet were the most frequently treated site of facial wrinkles. Average number of treated sites were 2.38. Side effect profiles were similar as previous reports in Cauca sians. The number of patients who took the regular retreatment was less than expected.
CONCLUSION
The clinical profiles of wrinkle patients in Koreans treated with botulinum toxin A were assessed. We think it is one of the effective treatment modalities for antiwrinkling.

Keyword

Facial wrinkle; Expression muscles; Botulinum toxin

MeSH Terms

Age of Onset
Asian Continental Ancestry Group
Botulinum Toxins
Botulinum Toxins, Type A
Facial Expression*
Female
Follow-Up Studies
Foot
Humans
Male
Medical Records
Muscles*
Retreatment
Botulinum Toxins
Botulinum Toxins, Type A