J Korean Neurol Assoc.
2002 Jan;20(1):79-81.
Three Cases of Anticonvulsant Hypersensitivity Syndrome Associated with Lamotrigine
- Affiliations
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- 1Department of Neurology, Keimyung University, School of Medicine, Korea. neurocho@dsmc.or.kr
Abstract
- Among the various side effects of anticonvulsant medication, the anticonvulsant hypersensitivity syndrome (AHS) is underrecognized. This condition developed frequently with aromatic anticonvulsants, but with new antiepileptic drugs as well. We experienced three lamotrigine-induced AHS cases with symptoms such as fever, rash, leukopenia, eosinophilia and lymphadenopathy, which subsided after withdrawal of lamotrigine.
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