J Korean Radiol Soc.  2005 Aug;53(2):129-135. 10.3348/jkrs.2005.53.2.129.

Usefulness of Ultrasound-guided Mammotome Biopsy for Microcalcification

• Kim YM
• Park HB
• Ryu JW

• KMID: 1582442
• DOI: http://doi.org/10.3348/jkrs.2005.53.2.129

Abstract

PURPOSE
To evaluate the usefulness of ultrasound-guided mammotome biopsy for microcalcification and to suggest a new approach for the localization of microcalcifications which are not detected on ultrasound.
MATERIALS AND METHODS
Twenty-one calcific lesions in 21 women (aged 33-56 years) underwent ultrasound-guided, vacuum-assisted, mammotome biopsy and a mean of 14 specimens per lesion were obtained. Calcification retrieval was defined as identification of calcifications on specimen radiographs. In the 13 cases of calcifications which were not detected on ultrasound imaging, mammotome biopsy was performed after localization of one or two needles at the microcalcifications under mammography-guidance. Radiographs of the specimens and histologic findings were reviewed and scheduled follow-up imaging was performed for evaluation of the complications of biopsy.
RESULTS
Ultrasound-guided, vacuum-assisted, mammotome biopsy removed all calcifications in 21 lesions. Eight (38%) lesions showed visible calcification on the ultrasound while 13 (62%) lesions were invisible, which underwent mammotome biopsy after needle localization under mammography-guidance. Surgery revealed DCIS in 1 (4.8%) of 21 lesions, infiltrating ductal carcinoma in two (9.5%), fibroadenomas with calcifications in 6 (28.6%), fibroadenomas with adenosis in 2 (9.5%), and fibrocystic change with calcifications in 10 (47.6%). Clinical significant complications did not occur on follow-up examination in any of the cases.
CONCLUSION
Ultrasound-guided, vacuum-assisted, mammotome biopsy was an effective method for microcalcifications on mammogram. The results suggested that mammotome biopsy after mammogram-guided, needle localization is a good alternative method for the diagnosis of microcalcifications which are undetectable in the ultrasound images.

Keyword

Breast, biopsy; Breast neoplasms, localization; Breast neoplasms, US; Ultrasound (US), guidance

MeSH Terms

Biopsy*
Carcinoma, Ductal
Carcinoma, Intraductal, Noninfiltrating
Diagnosis
Female
Fibroadenoma
Follow-Up Studies
Humans
Needles
Ultrasonography