Korean J Cerebrovasc Surg.  2004 Mar;6(1):11-15.

Hemodynamic Pathogenesis of AVM

Affiliations
  • 1Department of Neurosurgery, Soonchunhyang University Hospital, Bucheon, Korea. bumtkim@sch.ac.kr

Abstract

Significantly decreased perfusion pressure is common in vascular territories irrigating neuronal tissue in patients with AVMs. There is evidence that "adaptive autoregulatory displacement" occurs in these patients which maintains cerebral blood flow above ischemic levels. Chronic arteriolar vasodilatation does not usually lead to vasomotor paralysis because most patients maintain a constant cerebral blood flow in spite of increased systemic arterial pressure. AVM hemodynamics appears to play an important role in the etiology of spontaneous intracerebral hemorrhage. Large AVM with high-flow and severe arterial hypotension are least likely to hemorrhage. In patients with AVMassociated aneurysm, the etiology of these dual lesions is likely multifactorial, with hemodynamic stresses having a dominant influence.

Keyword

Adaptive autoregulatory displacement; AVM hemodynamics

MeSH Terms

Aneurysm
Arterial Pressure
Cerebral Hemorrhage
Hemodynamics*
Hemorrhage
Humans
Hypotension
Neurons
Paralysis
Perfusion
Vasodilation
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