J Korean Soc Pediatr Nephrol.  2006 Apr;10(1):40-44.

A Case of Henoch-Schonlein Purpura with Hemorrhagic Bullae in a Child

Affiliations
  • 1Department of Pediatrics, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. jyjeong@uuh.ulsan.kr
  • 2Department of Pathology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.

Abstract

Henoch-Schonlein purpura(HSP) is a systemic small vessel vasculitis characterized by cutaneous purpura, arthritis, abdominal pain and nephritis. The characteristic rash of HSP consists of palpable purpura on the buttocks and lower extremities. Bullous lesions often appear in adults with HSP, whereas they are very rare in children with HSP. In this case report, the patient presented with arthralgia and abdominal pain and had hemorrhagic bullae as a prominent manifestation of the disease. The skin biopsy of the patient revealed typical leukocytoclastic vasculitis of dermal vessels and prominent IgA and fibrinogen deposits on capillary walls by direct immunofluorescence. We confirmed the diagnosis of HSP and observed improvement of clinical symptoms and signs within a few days after corticosteroid treatment. We therefore report a case with a review of the literature.

Keyword

Henoch-Schonlein purpura; Hemorrhagic bullae; Leukocytoclastic vasculitis; IgA; Fibrinogen

MeSH Terms

Abdominal Pain
Adult
Arthralgia
Arthritis
Biopsy
Blister
Buttocks
Capillaries
Child*
Diagnosis
Exanthema
Fibrinogen
Fluorescent Antibody Technique, Direct
Humans
Immunoglobulin A
Lower Extremity
Nephritis
Purpura
Purpura, Schoenlein-Henoch*
Skin
Vasculitis
Fibrinogen
Immunoglobulin A
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