J Korean Neurol Assoc.  2006 Jun;24(3):298-300.

Irreversible Parkinsonism due to Acute Organophosphate Intoxication

Affiliations
  • 1Department of Neurology, Hallym University College of Medicine, Seoul, Korea. neukwon@hallym.ac.kr

Abstract

Only a few case studies describe reversible parkinsonism after organophosphate poisoning and their brain imagings are found to be normal. However, we experienced chronic, irreversible parkinsonism by acute organophosphate poisoning with bilateral basal ganglia lesions found on a brain MRI. We suggest that brief, large amounts of organophosphate intoxication can produce irreversible parkinsonism according to individual susceptibility and further studies including the investigation of insecticides as an environmental factor of parkinsonism should be done using neuroimagings.

Keyword

Organophosphates; Parkinsonism; Neurotoxins

MeSH Terms

Basal Ganglia
Brain
Insecticides
Magnetic Resonance Imaging
Neurotoxins
Organophosphate Poisoning
Organophosphates
Parkinsonian Disorders*
Insecticides
Neurotoxins
Organophosphates
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