Cancer Res Treat.
2002 Dec;34(6):457-460.
A Case of Primary Gastric Choriocarcinoma Presenting with Amenorrhea
- Affiliations
-
- 1Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea. moisa @ewha.ac.krs
- 2Department of Gynecology, College of Medicine, Ewha Womans University, Seoul, Korea.
- 3Department of Pathology, College of Medicine, Ewha Womans University, Seoul, Korea.
Abstract
- Primary gastric choriocarcinomas are very rare, and their prognosis is extremely poor. A 37-year-old woman presented with amenorrhea, vaginal spotting and severe nausea, which mimicked a pregnancy and gestational trophoblastic disease. The serum level of the beta-subunit of human chorionic gonadotrophin (beta-hCG) was significantly increased. An endoscopic biopsy of the stomach mass showed the features of a choriocarcinoma, with marked anaplasia and necrosis. Immunohistochemical staining for beta-hCG showed positive results in the choriocarcinoma. Chemotherapy for the choriocarcinoma was administered, but she died 8 months following diagnosis.
