Korean J Gastrointest Endosc.  2001 Apr;22(4):245-249.

Primary Malignant Lymphoma of the Ampulla of Vater

Affiliations
  • 1Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. mhkim@www.amc.seoul.kr

Abstract

The vast majority of ampullary tumors are epithelial in nature and are either adenoma or adenocarcinoma. Rarely lymphoma or mucinous and squamous elements may be found. Primary lymphoma of pancreaticobiliary region are exceedingly rare, and mostly nodal. Recently, we have experienced a 29-year-old woman with primary malignant lymphoma of the ampulla of Vater with recurrent acute pancreatitis and jaundice. On duodenoscopy, bulging ampulla with normal overlying duodenal mucosa was observed. Endoscopic sphincterotomy was done and tumor inside the ampulla was exposed. ERCP showed high grade biliary and pancreatic ductal strictures extending from the papillary orifice, with upstream ductal dilatation, respectively. With endoscopic biopsy alone, the tumor was confirmed as B-cell lymphoma histologically.

Keyword

Primary lymphoma; Ampulla of Vater; Recurrent pancreatitis; Jaundice

MeSH Terms

Adenocarcinoma
Adenoma
Adult
Ampulla of Vater*
Biopsy
Cholangiopancreatography, Endoscopic Retrograde
Constriction, Pathologic
Dilatation
Duodenoscopy
Female
Humans
Jaundice
Lymphoma*
Lymphoma, B-Cell
Mucins
Mucous Membrane
Pancreatic Ducts
Pancreatitis
Sphincterotomy, Endoscopic
Mucins
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