Korean J Asthma Allergy Clin Immunol.  2007 Jun;27(2):131-135.

A Case of Occupational Asthma Caused by Alternaria Species

Abstract

Alternaria is a major aeroallergen in many countries of the world. Sensitivity to Alternaria is strongly associated with allergic rhinitits and asthma. We report a case of occupational asthma induced by exposure to Alternaria. A 26- year-old female who had been occupied in a pharmaceutical company for 6 years suffered from cough, chest discomfort, and dyspnea 2 months ago, and her symptoms were exacerbated after the work. Skin prick tests showed positive responses to D. pteronyssinus, D. farinae, Alternaria, Asper-gillus niger, and Candida albicans. Serum-specific IgE antibodies were detected only to Alternaria. Bronchoprovocation test to Alternaria showed dual asthmatic responses, and therefore she was definitively diagnosed with occupational asthma caused by Alternaria spp. These findings indicate that Alternaria can cause IgE-mediated occupational asthma.


MeSH Terms

Alternaria*
Antibodies
Asthma
Asthma, Occupational*
Candida albicans
Cough
Dyspnea
Female
Humans
Immunoglobulin E
Niger
Skin
Thorax
Antibodies
Immunoglobulin E
Full Text Links
  • KJAACI
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr