J Korean Diabetes Assoc.  2007 May;31(3):293-296. 10.4093/jkda.2007.31.3.293.

A Case of Ketosis-Prone Type 2 Diabetes Mellitus

Affiliations
  • 1Department of Internal Medicine, Konkuk University School of Medicine, Korea.

Abstract

Ketosis-prone type 2 diabetes (KPD) has been characterized as diabetes with severe insulin deficiency at diagnosis associated with ketosis or ketoacidosis without a precipitating cause. Improvement in beta-cell function and insulin sensitivity by aggressive diabetic management could allow discontinuation of insulin therapy within a few month of therapy. These subjects are usually obese, have a strong family history of diabetes, absence of beta-cell autoimmune markers and lack of human leukocyte antigen genetic association. This clinical presentation has been reported primarily in African and African Americans, but rare in Asian and white person. We recently experienced a case of KPD in Korea and present it with literature review.

Keyword

Diabetic ketoacidosis; Type 2 diabetes mellitus

MeSH Terms

African Americans
Asian Continental Ancestry Group
Diabetes Mellitus, Type 2*
Diabetic Ketoacidosis
Diagnosis
Humans
Insulin
Insulin Resistance
Ketosis
Korea
Leukocytes
Insulin

Figure

  • Fig. 1 Pelvic ultrasonography shows about 12 cm sized huge mass in uterus, suggesting adenomyosis.

  • Fig. 2 Colonoscopy shows several ulceration on the cecum.

  • Fig. 3 Nested polymerase chain reaction for Mycobacterium tuberculosis was done. One-hundred eighty-one base pair DNA was amplified at patient's sample. M, size marker (100 bp ladder); PC, positive control; NC, negative control; Pt, patient's sample.


Cited by  1 articles

A Case of Autoantibody-Positive Ketosis-Prone Diabetes Mellitus
Bora Yoon, Gyuri Kim, Jae Hyun Bae, Yu Jung Yun, Yong Ho Lee, Byung Wan Lee, Chul Woo Ahn, Bong Soo Cha, Hyun Chul Lee, Eun Seok Kang
J Korean Diabetes. 2016;17(1):60-66.    doi: 10.4093/jkd.2016.17.1.60.


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