J Korean Cleft Palate-Craniofac Assoc.  2007 Apr;8(1):20-22.

A Case of Sjogren Syndrome in Parotid Gland

• Park JW
• Kim HK
• Kim MS
• Ahn HS
• Kim JH
• Lee YM

Abstract

Sjogren syndrome is a chronic disorder characterized by immune-mediated destruction of exocrine glands predominantly but not exclusively on the lacrimal and salivary glands. The common clinical manifestations of Sjgren syndrome include xerophthalmia with secondary keratoconjunctivitis and xerostomia, with or without salivary gland enlargement. Minor salivary gland biopsy usually demonstrates heavy lymphocyte infiltration, although parotid gland biopsy may be more sensitive and specific. Rheumatoid factor and antinuclear antibodies are high in Sjgren syndrome patients. We report a case of Sjogren syndrome with parotid gland involvement in a 44-years-old female patient with xerostomia, xerophthalmia and Rheumatic arthritis. We did total parotidectomy in right parotid gland and superficial parotidectomy for left side parotid gland was done after 20 days. Histologic and immunohistochemical studies revelead multiple periductal lymphoid proliferation and chromic inflammation, lymphoid hyperplasia in parotid glands.

Keyword

Sjogren syndrome; Parotidectomy

MeSH Terms

Antibodies, Antinuclear
Biopsy
Exocrine Glands
Female
Humans
Hyperplasia
Inflammation
Keratoconjunctivitis
Lymphocytes
Parotid Gland*
Rheumatic Fever
Rheumatoid Factor
Salivary Glands
Salivary Glands, Minor
Sjogren's Syndrome*
Xerophthalmia
Xerostomia
Antibodies, Antinuclear
Rheumatoid Factor