J Korean Soc Magn Reson Med.
2004 Dec;8(2):86-93.
1H Magnetic Resonance Spectroscopy of Primary Central Nervous System Lymphoma
- Affiliations
-
- 1Department of Radiology, Kyungpook National University Hospital, Korea. knuhrad@yahoo.co.kr
Abstract
- PURPOSE
We evaluated 1H MR spectroscopy improves the preoperative diagnosis of diffuse infiltrative type of primary central nervous system lymphomas. MATERIALS AND METHODS: After review of conventional MR images and medical records, we retrospectively reviewed proton MR spectra in seven patients with primary central nervous system lymphoma diagnosed by means of biopsy. Relative ratio of choline (Cho), N-acetylaspartate (NAA), and lipid-lactate (Lip- Lac) to creatine (Cr) were measured for quantitative analysis. RESULTS: The average ratio of Cho/Cr was 1.80+/-0.95, NAA/Cr was 1.34+/-0.41, and Lip-Lac/Cr was 1.12+/-0.16. All cases of lymphomas showed increased Lip-Lac peak. Two case of mass forming lymphoma showed decreased NAA/Cr significantly, whereas five cases of lymphoma without mass formation showed preserved NAA/Cr. CONCLUSION: We thought the presence of Lip-Lac peak without significant reduction of NAA on the MR spectroscopy was helpful for diagnosis of diffuse infiltrative type of central nervous system lymphoma.
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- Primary Central Nervous System Lymphoma Mimicking Behcet's Disease
- MR Spectroscopy and Diffusion Weighted Imaging Findings of Primary Non-Hodgkin Lymphoma of the Breast: Two Case Reports
- Primary Central Nervous System Involvement in Peripheral T-Cell Lymphoma: A Case Report
- H MR Spectroscopy on Parkinson's-like Syndrome Induced by Manganese Intoxication: A Case Report
- Primary Central Nervous System Lymphoma Associated with Systemic Lymphoma: Case Report
