Nucl Med Mol Imaging.  2007 Feb;41(1):66-67.

18F-FDG PET/CT in POEMS Syndrome

  • 1Department of Nuclear Medicine and Molecular Imaging, Ajou University School of Medicine, Suwon, Korea.


POEMS syndrome is a rare disorder, also known as Crow-Fukase, PEP or Takatsuki syndrome. The acronym, POEMS, represents polyneuropathy, organomegaly, endocrinopathy, M protein and skin change. However, there are associated features not included in the acronym such as sclerotic bone lesions, Castleman disease, papilledema, thromobocytosis, peripheral edema, ascites, effusion, polycythemia, fatigue and clubbing. In most cases, osseous lesions in POEMS syndrome present as an isolated sclerotic deposit and that reveal as osteosclerotic myeloma. Several cases of 18F-FDG PET in multiple myeloma involvements were reported, but there was no previous literature that reported FDG PET findings in POEMS syndrome. We describe here a 66-year-old patient with POEMS syndrome who underwent 18F-FDG PET/CT image.


POEMS; 18FDG-PET; osteosclerotic myeloma
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