Clin Pediatr Hematol Oncol.
2008 Apr;15(1):17-21.
A Case of Compartment Syndrome Secondary to Leukemic Infiltration in Chronic Myeloid Leukemia Patient
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Korea University, Seoul, Korea. kwcl5609@korea.ac.kr
Abstract
- Compartment syndrome is a condition characterized by increased pressure within a closed space, leading to compression of nerves or blood vessels, usually associated with injury or surgery. Leukemic cells are present in bone marrow, liver, spleen and peripheral blood. But in rare cases, leukemic infiltration of muscle could be the cause of compartment syndrome. We report a case of 11-year-old chronic myeloid leukemia patient who presented with compartment syndrome secondary to leukemic infiltration of muscle. During the diagnostic workup of chronic myeloid leukemia, he complained of severe pain on right lower extremity, sensory and motor dysfunction and brownish skin discoloration. MR images showed extensive rhabdomyolysis and liquefaction of buttock, thigh adductor and hamstring muscles. Decompression operation was performed with emergency and then above symptoms improved. Muscle biopsy revealed leukemic infiltration with strong positive finding on myeloperoxidase, CD15 and chloroacetate esterase stain.
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