Tuberc Respir Dis.  2008 Mar;64(3):215-218. 10.4046/trd.2008.64.3.215.

Fatal Tumor Lysis Syndrome During Chemotherapy in Small Cell Lung Cancer

• Kook EH
• Kim MS
• Ahn SH
• Jeon SY
• Yoon JH
• Han MS
• Kim CH
• Lee JC

• KMID: 1478184
• DOI: http://doi.org/10.4046/trd.2008.64.3.215

Abstract

Tumor lysis syndrome is a life-threatening complication of anti-cancer therapy that typically occurs in patients with large, rapidly growing and treatment-sensitive tumors such as high-grade lymphomas and acute leukemias. However, its incidence in solid tumors has been known to be very low. Tumor lysis syndrome in solid tumors has a high mortality rate owing to the lack of prophylactic therapy to prevent this complication. We report a case of fatal tumor lysis syndrome developed during chemotherapy in extensive-stage small cell lung cancer, along with a brief review of the relevant literature considering the rarity of this manifestation in solid tumor.

Keyword

Small cell lung cancer; Tumor lysis syndrome

MeSH Terms

Humans
Incidence
Leukemia
Lymphoma, Non-Hodgkin
Small Cell Lung Carcinoma
Tumor Lysis Syndrome