Korean J Gastrointest Endosc.  2008 May;36(5):307-312.

Intestinal Amyloidosis Treated with High-Dose Steroids and Azathioprine: A Case Report

Affiliations
  • 1Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea. kwonjg@cu.ac.kr
  • 2Department of Pathology, Catholic University of Daegu School of Medicine, Daegu, Korea.

Abstract

Amyloidosis is a rare disease characterized by deposition and accumulation of insoluble fibrils in various organs and tissues. Variations in the precursor proteins composing each fibril account for the diverse character of amyloidosis. Amyloidosis light chain (AL) and amyloid A amyloidosis (AA) are two clinical entities representative of this diversity. We present a case of a 58-year-old woman presenting with refractory diarrhea and abdominal pain. She was ultimately diagnosed with intestinal amyloidosis diffusely involving the small and large intestines. Even though a definitive therapeutic strategy has not been established for gastrointestinal amyloidosis, this particular patient has been successfully managed with high-dose steroids and azathioprine.

Keyword

Intestinal amyloidosis; Steroid; Azathioprine
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