J Korean Neurosurg Soc.  2008 May;43(5):246-249. 10.3340/jkns.2008.43.5.246.

Pituitary Apoplexy due to Pituitary Adenoma Infarction

Affiliations
  • 1Department of Neurosurgery, Kyung Hee University Hospital, Seoul, Korea. hyunsong@khmc.or.kr

Abstract

Cause of pituitary apoplexy has been known as hemorrhage, hemorrhagic infarction or infarction of pituitary adenoma or adjacent tissues of pituitary gland. However, pituitary apoplexy caused by pure infarction of pituitary adenoma has been rarely reported. Here, we present the two cases pituitary apoplexies caused by pituitary adenoma infarction that were confirmed by transsphenoidal approach (TSA) and pathologic reports. Pathologic report of first case revealed total tumor infarction of a nonfunctioning pituitary macroadenoma and second case partial tumor infarction of ACTH secreting pituitary macroadenoma. Patients with pituitary apoplexy which was caused by pituitary adenoma infarction unrelated to hemorrhage or hemorrhagic infarction showed good response to TSA treatment. Further study on the predisposing factors of pituitary apoplexy and the mechanism of infarction in pituitary adenoma is necessary.

Keyword

Pituitary apoplexy; Pituitary adenoma infarction

MeSH Terms

Adrenocorticotropic Hormone
Hemorrhage
Humans
Infarction
Pituitary Apoplexy
Pituitary Gland
Pituitary Neoplasms
Adrenocorticotropic Hormone
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