Korean J Nephrol.
2008 Sep;27(5):611-615.
A Case of Interstitial Pneumonitis Associated with Sirolimus Treatment in Renal Transplantation Recipient
- Affiliations
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- 1Department of Internal Medicine, ASAN Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. skpark@amc.seoul.kr
Abstract
- Sirolimus is a promising immunosuppressive drug for renal transplantation to avoid nephrotoxicity of calcineurin inhibitor. However, it has been associated with uncommon but, important pulmonary toxicity. We present a case of sirolimus related dyspnea with abnormal chest radiographic finding in a 63 year old male renal transplantation recipient. There was no evidence of bacterial, fungal, or viral infection. Dose reduction of sirolimus resulted in a significant improvement of the symptoms and chest radiographic finding.
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