Korean J Nephrol.
2008 Nov;27(6):733-737.
Concurrent IgA Nephropathy and Minimal Change Disease in a Patient with Polycythemia Vera: A Case Report
- Affiliations
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- 1Department of Internal Medicine, Seoul Veterans Hospital, Seoul, Korea. glom@hanafos.com
- 2Department of Laboratory Medicine, Seoul Veterans Hospital, Seoul, Korea.
- 3Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Abstract
- Polycythemia vera is a hematopoietic stem cell disease, characterized by sustained and excessive proliferation of erythrocytic, granurocytic and megakaryocytic cells in the bone marrow resulting in pancytosis in peripheral blood. There have been a few reports of glomerulonephritis with polycythemia vera, most of which were IgA nephropathy. We report a case of a polycythemia vera associated with proteinuria. We confirmed the polycythemia vera according to World Health Organization criteria. Renal pathology showed IgA nephropathy and minimal change disease. Periodic phlebotomy was done and hydroxyurea was administered without specific managements for renal disease. After 3-month treatment, hemoglobin level decreased and proteinurea disappeared.
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