Korean J Nephrol.  2008 Nov;27(6):720-725.

IgA Nephropathy Encountered in a Patient with Hodgkin Lymphoma

• Yoo C
• Choi YJ
• Shim SI
• Lee K

Abstract

Various types of glomerulonephritis can occur at the same time with Hodgkin lymphoma, including minimal change disease and membranous glomerulonephritis. However, the concurrence of IgA nephropathy with Hodgkin lymphoma is rare. We report here on a case of IgA nephropathy in a patient with newly diagnosed Hodgkin lymphoma: A 60-year-old man presented with weight loss and anorexia. The patient showed lymphadenopathies in the neck on physical examination, and multiple lymphadenopathies in the mediastinum and abdomen on computerized tomography. Diagnosis of Hodgkin lymphoma was made after cervical lymph nodes were excised, but during the course of the chemotherapy, laboratory findings of hematuria and an elevated creatinine level were observed and IgA nephropathy was additionally diagnosed from a renal biopsy. There were fluctuations in the creatinine level and the amounts of hematuria and proteinuria, but by the time of the eighth cycle of chemotherapy, the patients condition had rapidly deteriorated, mainly due to the newly developed adult respiratory distress syndrome. The patient died soon thereafter.

Keyword

Hodgkin lymphoma; IgA nephropathy; Lymphadenopathy; Hematuria

MeSH Terms

Abdomen
Anorexia
Biopsy
Creatinine
Glomerulonephritis
Glomerulonephritis, IGA
Glomerulonephritis, Membranous
Hematuria
Hodgkin Disease
Humans
Immunoglobulin A
Lymph Nodes
Lymphatic Diseases
Lymphoma
Mediastinum
Middle Aged
Neck
Nephrosis, Lipoid
Physical Examination
Proteinuria
Respiratory Distress Syndrome, Adult
Weight Loss
Creatinine
Immunoglobulin A