Korean J Hepatobiliary Pancreat Surg.
2009 Jun;13(2):114-119.
Composite Large Cell Neuroendocrine Carcinoma and Adenocarcinoma of the Ampulla of Vater
- Affiliations
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- 1Department of Surgery, Holy Family Hospital,The Catholic University of Korea, Seoul, Korea. parkiy@catholic.ac.kr
- 2Department of Internal medicine, Holy Family Hospital,The Catholic University of Korea, Seoul, Korea.
- 3Department of Pathology, Holy Family Hospital,The Catholic University of Korea, Seoul, Korea.
Abstract
- Large Cell Neuroendocrine Tumors (LCNEC) in the ampulla of Vater are extremely rare. This report addresses a case of concurrent LCNEC and adenocarcinoma in the ampulla of Vater. A 60-year-old male patient experienced fever, body chills and jaundice. He had a periampullary ulcerative lesion and underwent radical pancreaticoduodenectomy. Histopathologically, the tumor consisted of an LCNEC component and an adenocarcinoma component. Simultaneous LCNEC and adenocarcinoma has been reported in a few cases. Our patient had a coexisting LCNEC and an adenocarcinoma of the ampulla of Vater. We also present a review of the literature
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