Korean J Nephrol.  2009 Mar;28(2):161-165.

A Case of a Kidney Transplant Recipient with Pulmonary Cytomegalovirus and Nocardia Coinfection with Cytomegalovirus Nephropathy

Affiliations
  • 1Department of Nephrology, Ajou University School of Medicine, Suwon, Korea. gtshin@ajou.ac.kr
  • 2Department of Pathology, Ajou University School of Medicine, Suwon, Korea.
  • 3Department of Pulmonary and critical Care Medicine, Ajou University School of Medicine, Suwon, Korea.

Abstract

This is the first reported case of a kidney transplant patient in Korea who developed cytomegalovirus and Nocardia pulmonary coinfection simultaneously with cytomegalovirus nephropathy. The patient had a history of end stage renal disease on peritoneal dialysis, diabetes mellitus and pulmonary tuberculosis. He underwent unrelated living kidney transplantation in China. About 5 months after transplantation, he developed high fever and rising serum creatinine for which he was admitted to hospital. Chest CT revealed consolidation in the left upper lung field and lung biopsy showed CMV infected bronchiolitis obliterans with organizing pneumonia. Culture of lung biopsy tissue grew Nocardia farcinica. In addition, he was found to have CMV infection in kidney tissue with positive CMV antigen assay of blood. This case emphasizes that CMV infection, through its effect on systemic immunity, may increase the risk of other opportunistic infection.

Keyword

Cytomegalovirus; Nocardia; Kidney transplantation

MeSH Terms

Biopsy
Bronchiolitis Obliterans
China
Coinfection
Creatinine
Cytomegalovirus
Diabetes Mellitus
Fever
Humans
Kidney
Kidney Failure, Chronic
Kidney Transplantation
Korea
Lung
Nocardia
Opportunistic Infections
Peritoneal Dialysis
Pneumonia
Thorax
Transplants
Tuberculosis, Pulmonary
Creatinine
Full Text Links
  • KJN
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
    DB Error: unknown error