J Lung Cancer.  2009 Jun;8(1):1-7. 10.6058/jlc.2009.8.1.1.

Management of Locally Advanced Non-small Cell Lung Cancer

  • 1Department of Radiation Oncology, UT Southwestern Medical Center at Dallas, Dallas, USA. Hak.Choy@UTSouthwestern.


Locally advanced Non-small cell lung cancer (NSCLC) is a commonly encountered diagnosis. Historically the treatment of locally advanced NSCLC has involved radiation therapy. Clinical trials have shown a benefit to the addition of chemotherapy. In recent years studies have further defined the role of chemotherapy by provided data showing the benefit of concurrent chemotherapy and radiation therapy followed by consolidation with more chemotherapy. Technological advances in radiation therapy have made dose escalation feasible and the current treatment paradigm is now evolving further as dose escalation data becomes available.


Non-small cell lung cancer; Combined modality therapy

MeSH Terms

Carcinoma, Non-Small-Cell Lung
Combined Modality Therapy
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