Korean J Otorhinolaryngol-Head Neck Surg.
2010 Feb;53(2):121-125. 10.3342/kjorl-hns.2010.53.2.121.
A Case of Tramadol Induced Asthma Attack in a Patient with Samter's Triad
- Affiliations
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- 1Department of Otolaryngology -Head and Neck Surgery, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. entr1@naver.com
- KMID: 1455721
- DOI: http://doi.org/10.3342/kjorl-hns.2010.53.2.121
Abstract
- Samter's triad is a well known syndrome and is characterized by a triad of asthma, aspirin or NSAID sensitivity and chronic sinusitis with nasal polyp. Chronic sinusitis with Samter's triad is difficult to treat completely and has poor prognosis. Tramadol is a non-opioid analgesic that rarely shows respiratory suppression and is known to be relatively safe because it does not inhibit prostaglandin synthesis. For that reason, patients with asthma may avoid drug-induced exacerbations of the disease by substituting Tramadol for NSAIDs. We experienced a case of asthma attack in a patient with Samter's triad after Tramadol injection.
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